Participate in a study!

Other bladder dysfunction information below

We are looking for participants for the following studies. If you are interested, please email our research coordinator with "Interest in study participation" in the subject line.

MS Bladder (NCT06072703)

This phase II randomized double-blind clinical trial is designed to evaluate the therapeutic effects of repetitive transcranial magnet stimulation (rTMS) in improving neurogenic overactive bladder (NOAB) in multiple sclerosis (MS) patients with a commercially available device. The target population for this study is adult patients (≥ 18 years old) with clinically stable MS who have been experiencing NOAB symptoms for more than 3 months. If you are interested, please contact us!

Individualized Tibial Neuromodulation at Home for Restoration of Bladder Function in Multiple Sclerosis

This pilot feasibility study is designed to evaluate the safety, feasibility, and preliminary effectiveness of individualized, home-based tibial neuromodulation (implantable or transcutaneous) in improving overactive bladder symptoms in people with multiple sclerosis, while also using functional MRI to investigate how this therapy restores brain-bladder connectivity. The target population for this study is adult patients with multiple sclerosis or a related demyelinating disease who have bothersome overactive bladder symptoms. If you are interested, please contact us!

Non-invasive brain neuromodulation in men for management of incontinence after prostate treatment: a proof-of-concept study

This phase I proof-of-concept study is designed to evaluate the safety, tolerability, and feasibility of a single session of repetitive transcranial magnetic stimulation (rTMS) targeted at the brain region controlling the pelvic floor, and to compare how excitatory versus inhibitory stimulation affects pelvic floor muscle tone and brain activity, in men with incontinence after prostate treatment. The target population for this study is adult men (18-80 years old) with a history of prostate cancer treatment who have persistent urinary incontinence at least 6 months after their procedure. If you are interested, please contact us!

Identification of Supraspinal Regions of Interest in Underactive Bladder

This prospective observational study is designed to identify and characterize the brain regions and functional connectivity patterns involved in bladder control in adults with underactive bladder (UAB), using a high-resolution, non-invasive functional MRI (fMRI) scan during natural bladder filling. The target population for this study is adult men and women (≥ 18 years old) with signs and symptoms of underactive bladder; healthy adult women (40 years and older) are also being recruited as a comparison group. If you are interested, please contact us!

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Urine Biobank Registry for Neurogenic Lower Urinary Tract Dysfunction (NLUTD) Urodynamic Studies

This study is a urine biobank registry designed to collect and store urine samples that would otherwise be discarded during routine urodynamic testing, linking them to clinical data to support future research into biomarkers for neurogenic lower urinary tract dysfunction (NLUTD), there is no additional visit, procedure, or intervention involved. The target population for this study is adult patients (≥ 18 years old) with NLUTD. If you are interested, please contact us!

Home Neuromodulation for Neurogenic Bladder Management in Spinal Cord Injury: A Hybrid Implementation-Efficacy Trial

This three-arm randomized trial is designed to evaluate the safety, feasibility, and effectiveness of the Injectrode, a minimally invasive implantable tibial nerve stimulation device, for reducing overactive bladder medication use and improving bladder function in people with spinal cord injury (SCI), while also using functional MRI to explore how this therapy changes brain and spinal cord activity. The target population for this study is adult men and women (18-75 years old) with chronic, non-progressive SCI at neurologic level T9 or above who are on a stable dose of overactive bladder medications. If you are interested, please contact us!

Resources for Understanding Bladder Dysfunction

Augmentation Cystoplasty

Dr. Rose Khavari

Multiple Sclerosis Bladder Issues

Dr. Rose Khavari

INUS Neuro-Urology News Interview with Dr. Rose Khavari

Dr. Rose Khavari

Participate in a study! Other bladder dysfunction information below

MS Bladder (NCT06072703)

Individualized Tibial Neuromodulation at Home for Restoration of Bladder Function in Multiple Sclerosis

Non-invasive brain neuromodulation in men for management of incontinence after prostate treatment: a proof-of-concept study

Identification of Supraspinal Regions of Interest in Underactive Bladder

Urine Biobank Registry for Neurogenic Lower Urinary Tract Dysfunction (NLUTD) Urodynamic Studies

Home Neuromodulation for Neurogenic Bladder Management in Spinal Cord Injury: A Hybrid Implementation-Efficacy Trial

Resources for Understanding Bladder Dysfunction

Participate in a study!

Other bladder dysfunction information below